Creatine monohydrate evidence, 2018

Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D, Experimental Gerontology, 2018 — systematic review of creatine and cognitive tasks

Grade

BB — one solid RCT or consistent meta-analytic signal

Design

systematic review

Year

2018

Participants

281

Ingredient

Creatine monohydrate

Goal

Focus

Effect

Across 6 RCTs, creatine supported short-term memory and reasoning performance; effects were clearest under metabolic stress (sleep loss, vegetarian diets) and inconsistent elsewhere.

Limitations and notes

We grade B for cognition: the signal is real but narrower than the strength evidence.

doi.org/10.1016/j.exger.2018.04.013

Cited by

• Creatine monohydrate monograph