Melatonin evidence, 2002

Herxheimer A, Petrie KJ, Cochrane Database of Systematic Reviews, 2002 — melatonin for jet-lag symptoms

Grade
Design
systematic review
Year
2002
Participants
not reported as a single figure
Ingredient
Melatonin
Goal
Sleep

Effect

Nine of ten trials found melatonin taken near destination bedtime reduced jet-lag ratings after flights crossing five or more time zones.

Limitations and notes

The clearest use case: shifting sleep timing, not deepening sleep.

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